Pulmonary vasoconstrictor action of KCNQ potassium channel blockers. Respir Res. Jackson WF. Potassium channels in the peripheral microcirculation. Vascular KCNQ potassium channels as novel targets for the control of mesenteric artery constriction by vasopressin, based on studies in single cells, pressurized arteries, and in vivo measurements of mesenteric vascular resistance. J Pharmacol Exp Ther. Functional up-regulation of KCNA gene family expression in murine mesenteric resistance artery smooth muscle. Nomenclature and molecular relationships of calcium-activated potassium channels.
Endothelial small-conductance and intermediate-conductance KCa channels: an update on their pharmacology and usefulness as cardiovascular targets. J Cardiovasc Pharmacol. J Biol Chem. Small-conductance calcium-activated potassium channels. Ann N Y Acad Sci. Mechanism of calcium gating in small-conductance calcium-activated potassium channels. Pflugers Arch.
Genetic deficit of SK3 and IK1 channels disrupts the endothelium-derived hyperpolarizing factor vasodilator pathway and causes hypertension. Functional architecture of inositol 1,4,5-trisphosphate signaling in restricted spaces of myoendothelial projections.
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Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis. Vascular KCa-channels as therapeutic targets in hypertension and restenosis disease. Expert Opin Ther Targets.
Calcium-activated potassium channels contribute to human coronary microvascular dysfunction after cardioplegic arrest. The intermediate-conductance calcium-activated potassium channel KCa3. J Clin Invest. Pharmacology and structure of high conductance calcium-activated potassium channels. Cell Signal. Functionally diverse complement of large conductance calcium- and voltage-activated potassium channel BK alpha-subunits generated from a single site of splicing.
Alternative splicing switches potassium channel sensitivity to protein phosphorylation.
Vasoregulation by the beta1 subunit of the calcium-activated potassium channel. Relaxation of arterial smooth muscle by calcium sparks. Functional coupling of ryanodine receptors to KCa channels in smooth muscle cells from rat cerebral arteries. J Gen Physiol. Large and small conductance calcium-activated potassium channels in the GH3 anterior pituitary cell line. McManus OB.
Calcium-activated potassium channels: regulation by calcium. J Bioenerg Biomembr. Properties of single calcium-activated potassium channels in cultured rat muscle. Arachidonic acid metabolites as endothelium-derived hyperpolarizing factors. Calcium-activated potassium channels and endothelial dysfunction: therapeutic options? Elevated blood pressure linked to primary hyperaldosteronism and impaired vasodilation in BK channel-deficient mice.
Hypercontractility and impaired sildenafil relaxations in the BKCa channel deletion model of erectile dysfunction. Erectile dysfunction in mice lacking the large-conductance calcium-activated potassium BK channel. Downregulation of the BK channel beta1 subunit in genetic hypertension. Functional and molecular evidence of MaxiK channel beta1 subunit decrease with coronary artery ageing in the rat.
Genetic variation in the KCNMA1 potassium channel alpha subunit as risk factor for severe essential hypertension and myocardial infarction. J Hypertens. Protective effect of the KCNMB1 E65K genetic polymorphism against diastolic hypertension in aging women and its relevance to cardiovascular risk. Acta Physiol Scand. Local potassium signaling couples neuronal activity to vasodilation in the brain. Nat Neurosci. Targeted disruption of Kir2. Functional expression of inward rectifier potassium channels in cultured human pulmonary smooth muscle cells: evidence for a major role of Kir2.
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Muscle tissue – Knowledge for medical students and physicians
Transgenic expression of a dominant negative K ATP channel subunit in the mouse endothelium: effects on coronary flow and endothelin-1 secretion. KATP channels are an important component of the shear-sensing mechanism in the pulmonary microvasculature. Enyedi P, Czirjak G.
Evidence for two-pore domain potassium channels in rat cerebral arteries. Functional evidence of a role for two-pore domain potassium channels in rat mesenteric and pulmonary arteries.
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Calcium Cycling in Synthetic and Contractile Phasic or Tonic Vascular Smooth Muscle Cells
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