Hybridomas and Cellular Immortality


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We have supported discovery projects for over 40 years.

After overcoming some technical difficulties, they successfully generated several hybridomas that secreted very large quantities of monoclonal antibodies. This paved the way for the early commercialization of monoclonal antibody technology. My account E-alert sign up Register Subscribe. Milestones timeline 1 2 3 4 5 6 7 8 9 10 11 12 13 Fusion of two immunoglobulin-producing myeloma cells.

Antibody with homogeneous antigen binding produced by splenic foci in organ culture. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.

Hybridoma Platform - Creative Biolabs

With deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions. Get a real taste of Creative Biolabs, one of the most professional custom service providers in the world.


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We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects. Creative Biolabs provides a full range of services based on our matured hybridoma platform. Our featured services involve the custom monoclonal antibody production, from gene expression or peptide synthesis to antibody purification and labeling. We have the capacity of producing antibodies in either research quantities or in large scale for diagnostic industry.

Rhodamine 123 fluorescence of immortal hybridoma cell lines as a function of glucose concentration

Importantly, we can produce monoclonal antibodies within 70 days. Creative Biolabs also has the expertise in handling antigen insufficiency and targeting very impure antigens.

About this book

Hybridoma technology is a method for the long-lasting production of large-scale monoclonal antibodies. The technology is based on the forming of hybrid cell line, which are immortalized cell derived from the fusion of specific antibody-producing B lymphoblast with myeloma. This can be explained by the previously described dependence of specific glucose consumption rates on glucose availability in the medium.

The importance of controlling glucose availability, especially in large scale fermentations, is discussed. The full text of this article hosted at iucr. If you do not receive an email within 10 minutes, your email address may not be registered, and you may need to create a new Wiley Online Library account. If the address matches an existing account you will receive an email with instructions to retrieve your username.


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Cytometry Volume 14, Issue 1. Original Article Free Access.

Making monoclonal antibodies

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Hybridomas and Cellular Immortality Hybridomas and Cellular Immortality
Hybridomas and Cellular Immortality Hybridomas and Cellular Immortality
Hybridomas and Cellular Immortality Hybridomas and Cellular Immortality
Hybridomas and Cellular Immortality Hybridomas and Cellular Immortality
Hybridomas and Cellular Immortality Hybridomas and Cellular Immortality
Hybridomas and Cellular Immortality Hybridomas and Cellular Immortality

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